1- Where are the plasma cells settled after the activity?
bone marrow
2- The expression of which cytokine causes T cell activity to continue?
Aikos
3-English question:
A man with low iga and igg but high igm, do you think the problem is in which option?
ISO type switching
4- Tumor antigen presented on MHC-1 is recognized by which cell?
1) Tc
2) TH
3) B cells
4) myeloid dendritic
5- If a person has platelet deficiency (thrombocytopenia), which possible treatment do you suggest?
1) GM-CSF
2) IL-10
3) IL-6
4) IL-11
6- What type of tolerance is acceptor editing in B cell tolerance?
1) Central T
2) T environment
3) Central B
4) Environment B
7- The defect in which antigen is less important in causing autoimmune disease?
1) FoxP3
2) CTLA-4
3) Fas/FasL
4) CD28
8- Which cell presents the tumor antigen to MHC-1?
1) TH
2) TC
3) B
4) myeloid dendritic
9- A person with digestive and respiratory infection goes to the doctor. The person’s serum antibody is normal, which one is far from expected?
Defects in TGF production
Defects in CD40 production
Complement defect
defect in
10- Which one has a lesser role in mucus?
IgG
11- X-chromosome dependent disease whose diagnostic test is nitrobuterazolium?
CGD
12- Which cytokine is dominant in the tuberculoid stage of Jazam disease?
13- Which cytokine receptor is defective in XCID?
14-Which cytokine has synergistic effects on the expression of MHC1 on the surface of cells with TNF?
1. IL-12
2. IL-9
3. IL-10
4. Interferon gamma
15- Which treatment do you recommend for a person suffering from platelet deficiency (thrombocytopenia)?
1. OM-CSF
2. IL-10
3-IL-6
4-IL-11
16- Where are M cells located?
1) Old plate
2) between epithelial cells
3) lamina propria
4) Mucus
17- Which factor plays a role in the development of central T tolerance?
1) AIRE gene expression
2) Energy
3) co-stimulatory molecules
18-Which cell works best in providing antigen to naive T cells
1-B cell
2- Macrophage
3- myeloid dendritic cell
4- Vascular endothelial
19-Inhibition of which protein prevents the spread of tumor?
1-Icos
2-PDL1
3-CD28
4-CD40
20-Which protein in B cell plays a role in affinity maturation and antibody class switching?
1) CD40L
2) CD40
3) CD19
4) CD20
21- A person comes with digestive and respiratory infections. In the laboratory examination, the level of serum antibodies and other blood cells is normal. Which complication regarding the immune system of a person is not likely?
1) It is defective in TGF production
2) It is defective in sIgA production
3) There is a defect in the CD40 gene
4) There is a defect in the complement system
22- In the topic of cancer immunotherapy, which cell plays a greater role in antigen presentation and immune stimulation?
1) Dendritic cell
2) Macrophage
3) B cell
4) TH1
23-Which characteristic of IEL cells in humans is correct?
1) About 10% of them have gamma delta receptors.
2) Most of them are CD4+ type.
3) They have receptors with high diversity.
4) They are a dedicated safety component.
24-Which one stimulates the macrophage to secrete No.?
INFgamma
INFalpha
TNF
Option A and C
25-Which proteins in B cells have an effect on the processes of maturation and affinity?
26- Plasma cells resulting from secondary immune responses are more in which part?
27-Which antibody plays a lesser role in mucosal immunity?
1) IgG
2) M pentamer
3) M monomer
4) AgA dimer
28-Which PRR is an inflammatory index?
1) MBL
2) sab
3) CRP
4) Complement
29-Which one of the following receptors recognizes the DNA sequence in bacteria?
1) TLR-7
2) TLR-9
3) TLR-3
4) TLR-8
Descriptive questions:
1) Which cytokines can be regulated in the body?
2) Which cytokines are endocrine?
3) What is the disease related to keratinocytes and inflammation?
4) Which cytokine has a synergistic effect?
5) Which of the cytokines has redundancy with interleukin 2 in NK proliferation?
6) IgM increases in disease, what is the defect?
#Medicine 1400
#Safety
Yazd Shahid Sadoughi University of Medical Sciences