#Gentamox
(GENTAMOX)
Pharmaceutical group
Antibiotic – injectable sterile suspension
Medicinal composition
Amoxicillin (trihydrate) 150 mg/ml
Gentamicin (sulfate) 40 mg/ml
Oily expans up to a volume of one milliliter
Mechanism of action
Due to the synergistic effects of gentamicin and amoxicillin, this drug acts as a broad-spectrum bactericidal antibiotic. Amoxicillin is effective against gram-positive and gram-negative bacteria. This substance prevents the synthesis of the bacterial wall. Gentamicin is an aminoglycoside compound that has a broad-spectrum and fast action and mainly acts as an inhibitor of protein synthesis in the ribosome of bacteria. The destruction of the bacterial wall following the action of amoxicillin allows better penetration of gentamicin into so that a better result is obtained in lower doses.
Drug feature
This drug has stability and suitable injection ability. The raw and active ingredients of Gentamox are microionized, and the use of a special excipient provides a stable product with excellent release capabilities. Due to the use of this medicine, there are no negative reactions at the injection site, and the suspension stability of this product is higher than other similar products. Pharmacokinetic studies conducted on Gentamox have proven that this product has high bioavailability. This means that the therapeutic concentration of this drug remains in the blood for a longer period of time, which is related to the oil excipient and the characteristics of the antibiotics used. As a result, unlike most products formulated with gentamicin that must be used every 8 to 12 hours, this drug can be used every 24 hours.
Use cases
Cattle: pneumonia, diarrhea, intestinal microbial inflammation, mastitis, metritis and skin abscesses
Webb’s sheep: pneumonia, diarrhea, microbial inflammation of the intestine, pasteurosis and colibacillosis
Horses: Pneumonia, diarrhea, microbial enteritis, urinary tract infection, strangles, skin abscesses, and locomotor infections.
Method of consumption
Intramuscular (IM) injection
Amount of consumption
Cow: 30-40 ml per day
Calf: 10-15 ml per day
Adult horse: 30-50 ml per day
Foal: 5-15 ml per day
Adult sheep and goats: 5-10 ml per day
Lamb and goat: 1-5 ml per day
According to the opinion of the veterinarian, 1 milliliter per 10 kg of body weight for three days
Note: At the time of administration in large volumes in horses and cattle, it is better to inject in two areas to better absorb the drug.
Prohibition period
Meat: 30 days
Milk: 2 days
Precautions
Shake the medicine bottle well before use. If the bottle stays still for a while, a two-phase solution may be formed, which easily turns into a suspension after shaking.
In case of poisoning due to increased dosage, stop taking the drug and provide a supportive treatment. In order to prevent this problem, the dosage of this drug should not be more than 3 ml per 10 kg of body weight.
Drug interaction
No cases have been reported so far.
Side effects
Long-term treatment with higher than recommended doses may lead to kidney failure.
Storage conditions
Store in a cool place away from light.
packaging
100 ml vial
Iran’s Romanov market
This post is written by hosseinidirector