Identification of appetite controlling cells in the brain

Identification of appetite controlling cells in the brain

Neurosafari With research conducted at the University of Warwick, cells to control appetite have been identified in the human brain. This finding can make dramatic changes in the basis of diet design.
According to Neurosafari, quoting the news department of Warwick University, for the first time, Dr. Nicholas Dale was able to discover tanycytes in the College of Life Science, which control the energy level in the brain. These cells are responsible for identifying nutrients in food and reporting it to the brain.
According to this research, “tanycytes” cells in the brain are sensitive to the amino acids in the consumed food and measure the amount of amino acid with the same receptors that are present in the taste cells called “umami” (specific to the taste of umami). they take
Feel less hungry
“Arginine” and “Lysine” amino acids have the greatest effect on “tanycytes” cells, that is why a person experiences a feeling of fullness by consuming them. Foods such as beef, steak, chicken, mackerel fish, plums, apricots, avocados, lentils and almonds are rich in these two amino acids, which make you feel less hungry.
By adding a specific and concentrated amount of Arginine and Lysine impregnated with a fluorescent substance (to be identified through a microscope) to the brain cells, the researchers observed that these two amino acids through tanycytes cells in less than thirty seconds after Consumption is detected and reported to the part of the brain responsible for controlling appetite and weight. They investigated the signals received by taste receptor cells from amino acids and found that by blocking or eliminating umami taste receptors, tanycyte cells no longer respond to amino acids.
Obesity treatment and appetite control in the near future
Nicholas Dale, professor of neurology at Warwick University, added: “Signals caused by the amount of amino acids in the blood play an important role in our feeling of satiety, and finding Tanycyte cells in the center of the appetite control part of the brain can lead to the discovery of ways to be new in helping obese people without special side effects.” This great discovery opens the door to designing more beneficial diets and even treating obesity by suppressing appetite with direct stimulation.
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