Identifying commonalities between Alzheimer’s, Parkinson’s and Huntington’s/one treatment for three diseases
Neurosafari Abnormal proteins found in Alzheimer’s, Parkinson’s and Huntington’s diseases have a similar ability to cause damage when attacking brain cells, a study has found. The findings show that an effective treatment for one of these nerve-damaging diseases can be effective and efficient for other nerve-damaging diseases.
According to Neurosafari, citing the website of Loyola University, these findings can probably explain the mechanism of the spread of Alzheimer’s, Parkinson’s and Huntington’s diseases and other destructive diseases of the central nervous system, as well as the reason for the disruption of normal brain functions. The findings also show that an effective treatment for one of these neurodegenerative diseases can be effective for other neurodegenerative diseases as well. The study, conducted by Dr. Edward Campbell and Dr. William Flavin and their colleagues, was published in the journal Acta Neuropathologica. Campbell stated that: “Possible treatment could include enhancing the ability of brain cells to break down large amounts of damaged proteins and vesicles. If we can do this for one disease, then we have found a good treatment that can be effective for two other diseases as well.”
Neurodegenerative diseases cause the death of neurons and other cells in the brain, and in this regard, different diseases affect different areas of the brain. Alzheimer’s causes memory loss, while Parkinson’s and Huntington’s affect the motor parts of the brain. All three of these diseases are progressive, debilitating and incurable. Previous studies indicate that in these diseases, there are abnormal proteins that are accumulated in a massive way inside the brain cells. These protein masses spread from one cell to another and cause the death of other cells. Different proteins have been identified in each of these diseases: tau in Alzheimer’s, alpha-synuclein in Parkinson’s and huntingtin protein in Huntington’s disease.
The Loyola University study focused on how these “misfolded” proteins invade healthy brain cells. Researchers have observed that when these proteins are made inside the cell, they enter vesicles (small components that are surrounded by membranes inside the cell). These proteins cause the destruction or disintegration of the vesicle membranes and thus the mentioned proteins can attack the cytoplasm and cause more functional defects. goo.gl/dHm6VF Join the Neurosafari brain and neuroscience telegram channel:
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This post is written by neurosafari