D increases the activity of natural killer cells and improves the phagocytosis ability of macrophages. The active form of vitamin D3 increases the production of cathelicidin. This antimicrobial peptide is produced to deal with viruses, bacteria and fungi and inside macrophages. Vitamin D3 receptors have been identified in peripheral monocytes of poultry. This vitamin is necessary for proper phagocytosis and cytotoxic activity of macrophage cells. In diets that lack sufficient amounts of vitamin D3, the function of the immune system is significantly reduced. Also, this vitamin is involved in regulating the growth and differentiation of all types of blood cells, including immune cells. Vitamin D plays a direct role in strengthening the innate immune system through other antimicrobial peptides, including AvBD, chCATH-1 and GAL-1, leading to an increase in the phagocytic activity of macrophages.
The role of magnesium in intracalferol
– Magnesium as a cofactor plays a role in 300 enzymes, this substance plays a role in the metabolism of amino acids, fats, sugars, bone calcium and vitamin D.
– Magnesium is the fourth most abundant cation in living organisms and the second mineral that forms bones.
Magnesium deficiency in broiler chickens leads to muscle weakness, imbalance, reduced growth and weakness in feathering. will be
– Magnesium deficiency in egg-laying birds leads to reduced egg production, convulsions and nervous symptoms.
– Birds that use magnesium supplements in their diet lay heavier eggs and have better shell quality.
– Magnesium, due to its anti-oxidative effects, leads to increased resistance and improved performance of broiler chickens in thermal stress.
Indications:
• Improvement of shell and egg production in commercial laying hens and mothers
• Reducing the risk of bone fractures and Cage Layer Fatigue Syndrome
• Prevention and improvement of bone abnormalities in meat poultry
• Preventing milk fever and improving the lactation period in livestock
• Strengthening the immune system in all species
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