Anti-Müllerian AMH hormone test
This hormone was initially studied in the topic of sexual differentiation. In the male fetus, anti-Müllerian hormone is produced by some testicular cells and prevents the development of Müllerian tubes. After birth, this hormone decreases in boys and increases again during puberty and decreases again after this period. In female fetuses, this hormone is produced by primary follicles and reaches its maximum level in pre-antral follicles. It cannot be measured at the birth of a female baby, but after puberty, it will remain at its highest level until the end of pregnancy, and at the time of menopause, it will decrease to such an extent that it cannot be measured.
A woman’s ovary has a relatively high reserve of follicles that was formed early in her life. Germ cells are surrounded by somatic cells and form primordial follicles. After maturation, the follicles enter the growing reserve and if they are saved under the influence of FSH hormone, they continue to grow, otherwise they are destroyed. One of the remaining follicles is selected to become an egg.
Antimulleri
Mullerian hormone is produced by the granulosa of primary and pre-antral follicles and has the following two functions:
It prevents the growth of other follicles and supports the ovarian reserve of the body.
By reducing sensitivity to FSH hormone, it inhibits the growth and selection of pre-antral follicles that are affected by this factor.
Ovarian reserve
The volume of the follicle reserve along with the quality of the available oocytes is called the ovarian reserve, which decreases the ovarian reserve and fertility ability under the influence of aging. Tests that determine the amount of ovarian reserve along with antimolar are: FSH (the best time is the third day of the sexual period), Inhibin B, estradiol.
Antimolar hormone is always tested to check infertile couples, determine ovarian reserve, respond to IVF, etc. This test being higher than the normal range can indicate polycystic disease and the possibility of ovarian stimulation syndrome.
Conditions for performing the antimolar test:
The test is in the form of a few cc of venous blood. There is no need for special conditions such as fasting or taking blood on a specific day of menstruation. Taking birth control pills has no effect on the test result
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